Abstract
The article provides data on the development of an experimental model of exogenous acetonemia in rats and the study of the effectiveness of the isotonic composition of electrolytes together with metabolites activators of the formation of oxaloacetate in the Krebs cycle – ketoglutaric and malic acids in the product for special medical purposes «Acetostop». It is shown that the administration of exogenous acetone leads to the development of ketonuria and sedation of animals, and the introduction of «Acetostop» prevents the development of acetonemic syndrome.