Keywords
paracetamol, acute poisoning, acute liver failure, Acetylcysteine
Abstract
Today, paracetamol poisoning is one of the most common and most dangerous types of drug poisoning. In Ukraine, the number of suicide attempts involving paracetamol in 2018 has doubled compared to 2017. The aim was to investigate the dynamics of clinical and laboratory indicators for severe paracetamol poisoning, complicated by the development of acute liver failure, and evaluate the effectiveness of antidotes and pharmacological remedies use. Case of severe paracetamol tablets poisoning in a 22 years old woman is considered. The treatments were conducted in the toxictherapeutic department of the hospital of emergency medical aid of the city of Mykolaiv in 2018. Data of clinical, laboratory, functional research methods was analysed.